Esophagitis in a high H. pylori prevalence area: severe disease is rare but concomitant peptic ulcer is frequent.

Esophagitis in a high H. pylori prevalence area: severe disease is rare but concomitant peptic ulcer is frequent.

Blog Article

BACKGROUND: Few data are available on the prevalence of Cleansing Foam erosive and severe esophagitis in Western countries.OBJECTIVE: To retrospectively determine the prevalence and the factors predicting erosive esophagitis and severe esophagitis in a large series of endoscopies in Spain.DESIGN: Retrospective observational study.

A multivariate analysis was performed to determine variables predicting severe esophagitis.SETTING: Databases of 29 Spanish endoscopy units.PATIENTS: Patients submitted to a diagnostic endoscopy during the year 2005.

INTERVENTIONS: Retrospective review of the databases.MAIN OUTCOME MEASUREMENTS: Esophagitis severity (graded according to the Los Angeles classification) and associated endoscopic findings.RESULTS: Esophagitis was observed in 8.

7% of the 93,699 endoscopies reviewed.Severe esophagitis (LA grade C or D) accounted for 22.5% of cases of the disease and was found in 1.

9% of all endoscopies.Incidences of esophagitis and those of severe esophagitis were 86.2 and 18.

7 cases per 100,000 inhabitants per year respectively.Male sex (OR 1.89) and advanced age (OR 4.

2 for patients in the fourth age quartile) were the only variables associated with severe esophagitis.Associated peptic ulcer was present in 8.8% of cases.

LIMITATIONS: Retrospective study, no data on individual proton pump inhibitors use.CONCLUSIONS: Severe esophagitis is an infrequent finding in Spain.It occurs predominantly in males and in older individuals.

Peptic ulcer disease Dough Sheeters is frequently associated with erosive esophagitis.